Cobalamin Binding and Cobalamin-Dependent Enzyme
نویسنده
چکیده
This work was presented in part at the meeting ofthe American Society of Human Genetics, San Diego, Calif., October 1977. Dr. Mellman and Dr. Willard are recipients of traineeships from the National Institutes of Health (T01-GM 02299). Dr. Mellman's present address is Laboratory of Cellular Physiology and Immunology, The Rockefeller University, New York 10021. Received for publication 18 May 1978 and in revised form 23 June 1978. 952 cell extracts. These results suggest that both the cbl C and cbl D mutations affect some enzymatic step(s) which converts newly taken up cobalamin to a form capable of being bound by the two cobalamindependent enzymes.
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